1azd: Difference between revisions

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[[Image:1azd.jpg|left|200px]]
{{Seed}}
[[Image:1azd.png|left|200px]]


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{{STRUCTURE_1azd|  PDB=1azd  |  SCENE=  }}  
{{STRUCTURE_1azd|  PDB=1azd  |  SCENE=  }}  


'''CONCANAVALIN FROM CANAVALIA BRASILIENSIS'''
===CONCANAVALIN FROM CANAVALIA BRASILIENSIS===




==Overview==
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Canavalia brasiliensis lectin was isolated from the seeds of a Brazilian autochthonous Leguminosae plant. Despite extensive amino acid sequence similarity with Concanavalin A, C. brasiliensis lectin exerts in vitro and in vivo cellular effects that are markedly different from those displayed by Concanavalin A. We have solved the crystal structure of the C. brasiliensis lectin at 3.0 A resolution. The three-dimensional structure of the lectin monomer can be superimposed onto that of Concanavalin A with a root-mean-square deviation for all C alpha atoms of 0.65 A. However, this parameter is 0.84 and 1.62 A when the C. brasiliensis lectin dimer and tetramer, respectively, are compared with the same structures of Concanavalin A. We suggest that these differences in quaternary structure may account for the different biological properties of these two highly related Leguminosae lectins.
The line below this paragraph, {{ABSTRACT_PUBMED_9094437}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 9094437 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9094437}}


==About this Structure==
==About this Structure==
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[[Category: Sanz-Aparicio, J.]]
[[Category: Sanz-Aparicio, J.]]
[[Category: Legume lectin]]
[[Category: Legume lectin]]
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