6qno: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[6qno]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/ ] and [~~http~~://en.wikipedia.org/wiki/~~Bos_taurus Bos taurus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QNO OCA]. For a guided tour on the structure components use [~~http~~://proteopedia.org/fgij/fg.htm?mol=6QNO FirstGlance].

<table><tr><td colspan='2'>[[6qno]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QNO OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=6QNO FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.38Å</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://proteopedia.org/fgij/fg.htm?mol=6qno FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qno OCA], [~~http~~://pdbe.org/6qno PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6qno RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6qno PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6qno ProSAT]</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=6qno FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qno OCA], [https://pdbe.org/6qno PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qno RCSB], [https://www.ebi.ac.uk/pdbsum/6qno PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qno ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN]] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref> [[http://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref> [[http://www.uniprot.org/uniprot/GBG1_BOVIN GBG1_BOVIN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. [[http://www.uniprot.org/uniprot/GBB1_BOVIN GBB1_BOVIN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>

== Publication Abstract from PubMed ==

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==See Also==

*[[Antibody 3D structures|Antibody 3D structures]]

*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]

*[[Rhodopsin 3D structures|Rhodopsin 3D structures]]

*[[Transducin 3D structures|Transducin 3D structures]]

*[[3D structures of non-human antibody|3D structures of non-human antibody]]

== References ==

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</SX>

[[Category: Bos taurus]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Adaixo~~, R J~~]]

[[Category: Mus musculus]]

[[Category: Dawson~~, R J.P~~]]

[[Category: Adaixo RJ]]

[[Category: Deupi, X]]

[[Category: Dawson RJP]]

[[Category: Flock, T]]

[[Category: Deupi X]]

[[Category: Maeda, S]]

[[Category: Flock T]]

[[Category: Marino, J]]

[[Category: Maeda S]]

[[Category: Matile, H]]

[[Category: Marino J]]

[[Category: Mohammed, I]]

[[Category: Matile H]]

[[Category: Muehle, J]]

[[Category: Mohammed I]]

[[Category: Pamula, F]]

[[Category: Muehle J]]

[[Category: Schertler~~, G F.X~~]]

[[Category: Pamula F]]

[[Category: Stahlberg, H]]

[[Category: Schertler GFX]]

[[Category: Taylor~~, N M.I~~]]

[[Category: Stahlberg H]]

[[Category: Tsai, C J]]

[[Category: Taylor NMI]]

~~[[Category: Gpcr and g protein complex]]~~

[[Category: Tsai C-J]]

~~[[Category: Signaling protein~~]]

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@@ Line 3: / Line 3: @@
 <SX load='6qno' size='340' side='right' viewer='molstar' caption='[[6qno]], [[Resolution|resolution]] 4.38&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6qno]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QNO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6QNO FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6qno]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QNO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QNO FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.38&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6qno FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qno OCA], [http://pdbe.org/6qno PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qno RCSB], [http://www.ebi.ac.uk/pdbsum/6qno PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qno ProSAT]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qno FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qno OCA], [https://pdbe.org/6qno PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qno RCSB], [https://www.ebi.ac.uk/pdbsum/6qno PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qno ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN]] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref>  [[http://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>  [[http://www.uniprot.org/uniprot/GBG1_BOVIN GBG1_BOVIN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. [[http://www.uniprot.org/uniprot/GBB1_BOVIN GBB1_BOVIN]] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
+[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 20: / Line 21: @@
 ==See Also==
+*[[Antibody 3D structures|Antibody 3D structures]]
+*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
 *[[Rhodopsin 3D structures|Rhodopsin 3D structures]]
 *[[Transducin 3D structures|Transducin 3D structures]]
+*[[3D structures of non-human antibody|3D structures of non-human antibody]]
 == References ==
 <references/>
@@ Line 27: / Line 31: @@
 </SX>
 [[Category: Bos taurus]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Adaixo, R J]]
+[[Category: Mus musculus]]
-[[Category: Dawson, R J.P]]
+[[Category: Adaixo RJ]]
-[[Category: Deupi, X]]
+[[Category: Dawson RJP]]
-[[Category: Flock, T]]
+[[Category: Deupi X]]
-[[Category: Maeda, S]]
+[[Category: Flock T]]
-[[Category: Marino, J]]
+[[Category: Maeda S]]
-[[Category: Matile, H]]
+[[Category: Marino J]]
-[[Category: Mohammed, I]]
+[[Category: Matile H]]
-[[Category: Muehle, J]]
+[[Category: Mohammed I]]
-[[Category: Pamula, F]]
+[[Category: Muehle J]]
-[[Category: Schertler, G F.X]]
+[[Category: Pamula F]]
-[[Category: Stahlberg, H]]
+[[Category: Schertler GFX]]
-[[Category: Taylor, N M.I]]
+[[Category: Stahlberg H]]
-[[Category: Tsai, C J]]
+[[Category: Taylor NMI]]
-[[Category: Gpcr and g protein complex]]
+[[Category: Tsai C-J]]
-[[Category: Signaling protein]]