Sandbox Reserved 895: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Ivan E. Wang (talk | contribs) No edit summary |
Ivan E. Wang (talk | contribs) No edit summary |
||
| Line 10: | Line 10: | ||
For humans to see, the retinoid (visual) cycle converts incident light entering into the eye to electrochemical signals that can be transmitted to the brain as neuronal impulses. The chemical reactions that take place within the retinoid cycle allows the regeneration of key intermediates to allow for vision to take place. Dysregulation of these chemical processes, associated with disease, can lead to alterations in vision and blindness. Age related macular degeneration is an example of the dysregulation within the retinoid cycle. The 3-dimensional binding site of bovine RPE65 to an exogenous substrate (''R'')-emixustat shown in '''Figure 1''', was a tested drug treatment for dry age related macular degeneration. | For humans to see, the retinoid (visual) cycle converts incident light entering into the eye to electrochemical signals that can be transmitted to the brain as neuronal impulses. The chemical reactions that take place within the retinoid cycle allows the regeneration of key intermediates to allow for vision to take place. Dysregulation of these chemical processes, associated with disease, can lead to alterations in vision and blindness. Age related macular degeneration is an example of the dysregulation within the retinoid cycle. The 3-dimensional binding site of bovine RPE65 to an exogenous substrate (''R'')-emixustat shown in '''Figure 1''', was a tested drug treatment for dry age related macular degeneration. | ||
<StructureSection load='4rsc' size='500' side='right' caption='Figure 1: 3-dimensional bindging site of bovine RPE65 to (''R'')-Emixustat and palmitate ' scene=''> | |||
</StructureSection> | |||
= References = | = References = | ||
<references/> | <references/> | ||
