Sandbox Reserved 895: Difference between revisions

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The difference in bond lengths also confirms the increase in binding affinity and potency of the (R)-isomer. These interactions can be seen in '''Figure 9''' . <ref> DOI 26075817 </ref>
The difference in bond lengths also confirms the increase in binding affinity and potency of the (R)-isomer. These interactions can be seen in '''Figure 9''' . <ref> DOI 26075817 </ref>


[[Image:Figrue9_R_S_Emixustat_binding_pocket.jpg|thumb|center|512 px|alt=Figure 8ABCD: R and S Emixustat Binding Pocket| '''Figure 8:''' (''R'')-Emixustat and (''S'')-Emixustat in RPE65 binding pocket <ref> DOI 26075817 </ref>]]
[[Image:Figrue9_R_S_Emixustat_binding_pocket.jpg|thumb|center|512 px|alt=Figure 9ABCD: R and S Emixustat Binding Pocket| '''Figure 9:''' (A) Circular Dichroism on R, the (''R'')-isomer; M, the Racemic mixutre; and S, the (''S'')-isomer (B) Racemic emixustat bound to the RPE65 binding pocket (C) (''R'')-emixustat bound to the RPE65 binding pocket (D) (''S'')-emixustat bound to the RPE65 binding pocket <ref> DOI 26075817 </ref>]]