Sandbox Reserved 1600: Difference between revisions

The ''Geobacillus thermodenitrificans'' is a facultative aerobic thermophilic bacterium that utilizes the bd oxidase mechanism. The oxygen enters the enzyme through the selective <scene name='83/832926/Potential_oxygen_entry_site/1'>oxygen entry site</scene> that funnels the extracellular oxygen to <scene name='83/838655/Bd_oxidase_heme_d/1'>Heme D</scene> in the active site. The electrons for the reaction are provided by ubiquinone molecule bound to the <scene name='83/838655/Bdoxidase_q_loop/2'>Q loop</scene>. The protons for the reaction are provided by one of two <scene name='83/838655/Bdoxidase_proton_pathways/1'>potential proton pathways</scene>, either the <scene name='83/838655/Bdoxidase_cyda_pathway/6'>CydA pathway</scene>or <scene name='83/838655/Bdoxidase_cydb_pathway/3'>CydB pathway</scene>. Both of the proton pathways utilize the intracellular water molecules for the proton source, and shuttle them to <scene name='83/838655/Bd_oxidase_heme_b_595/1'>Heme B595</scene>.

<StructureSection  load='5DOQ'  size='350'  frame='true' side='right' caption='bd oxidase (PDB: [[5doq]])' scene='83/838655/Bdoxidase_structure_full/3'>

=Structure=