Sandbox Reserved 897: Difference between revisions
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== Overview == | == Overview == | ||
The PWWP domain belongs to the Royal family, which consists of Tudor, chromodomain, MBT, and PWWP domains. It was first identified as a structural motif includes 100 to 130 amino acids. The name PWWP comes after its very conservative sequence, Pro-Trp-Trp-Pro located at its β2 region. <ref>Chen T, Tsujimoto N, Li E. The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin. Molecular and cellular biology. 2004 Oct 15;24(20):9048-58.</ref> | The PWWP domain belongs to the Royal family, which consists of Tudor, chromodomain, MBT, and PWWP domains. It was first identified as a structural motif includes 100 to 130 amino acids. The name PWWP comes after its very conservative sequence, Pro-Trp-Trp-Pro located at its β2 region.<ref>Chen T, Tsujimoto N, Li E. The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin. Molecular and cellular biology. 2004 Oct 15;24(20):9048-58.</ref> | ||
== Function == | == Function == | ||
