User:Samuel Boyson/Sandbox 900: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 14: | Line 14: | ||
BRD has a similar sequence to other Bromodomains contained within family IV. The other proteins in family IV are: BRD9, BRPF3, BRPF1, BRPF1B, BRD1, ATAD2, and ATAD2B. Shown in Figure 2 is a sequence alignment between BRD7 and its closest related member of family IV, BRD9. The bromodomain sequence is 70 residues long for BRD7 and BRD9. For BRD7, the bromodomain sequence ranges from residue 148-218 while in BRD9 the sequence ranges from 153-223. Despite being the two most closely related bromodomains in family IV, BRD7 and BRD9 only share 71.83% sequence identity. | BRD has a similar sequence to other Bromodomains contained within family IV. The other proteins in family IV are: BRD9, BRPF3, BRPF1, BRPF1B, BRD1, ATAD2, and ATAD2B. Shown in Figure 2 is a sequence alignment between BRD7 and its closest related member of family IV, BRD9. The bromodomain sequence is 70 residues long for BRD7 and BRD9. For BRD7, the bromodomain sequence ranges from residue 148-218 while in BRD9 the sequence ranges from 153-223. Despite being the two most closely related bromodomains in family IV, BRD7 and BRD9 only share 71.83% sequence identity. | ||
[[Image:BRD7 BRD9 sequence alignment.png|600px| | [[Image:BRD7 BRD9 sequence alignment.png|600px|center|thumb]] | ||
== Implications in disease== | == Implications in disease== | ||
