6tqe: Difference between revisions

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<StructureSection load='6tqe' size='340' side='right'caption='[[6tqe]], [[Resolution|resolution]] 4.30&Aring;' scene=''>
<StructureSection load='6tqe' size='340' side='right'caption='[[6tqe]], [[Resolution|resolution]] 4.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6tqe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TQE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TQE FirstGlance]. <br>
<table><tr><td colspan='2'>[[6tqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TQE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yddA, yddA_3, DSI35_15825, ERS007665_02362, ERS007670_02474, ERS023446_03427, ERS027651_03600, ERS027652_02163, ERS027654_01933, ERS027656_03005, ERS027659_02286, ERS027661_01835, ERS027666_01377, ERS124361_03074, EZX46_07135, FDK60_09470, SAMEA2682835_03741, SAMEA2682864_01404, SAMEA2683035_00870 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tqe OCA], [http://pdbe.org/6tqe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tqe RCSB], [http://www.ebi.ac.uk/pdbsum/6tqe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tqe ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tqe OCA], [https://pdbe.org/6tqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tqe RCSB], [https://www.ebi.ac.uk/pdbsum/6tqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tqe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BACA_MYCTU BACA_MYCTU] Multi-solute ABC transporter that mediates uptake of unrelated hydrophilic compounds (PubMed:32296172). Can transport vitamin B12 and related corrinoids, and antimicrobial peptides such as bleomycin (PubMed:18996991, PubMed:32296172, PubMed:23407640). Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation (PubMed:32296172). Contributes to maintenance of chronic infections (PubMed:18996991).<ref>PMID:18996991</ref> <ref>PMID:23407640</ref> <ref>PMID:32296172</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Gati, C]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Guskov, A]]
[[Category: Gati C]]
[[Category: Rempel, S]]
[[Category: Guskov A]]
[[Category: Slotboom, D J]]
[[Category: Rempel S]]
[[Category: Abc transporter]]
[[Category: Slotboom DJ]]
[[Category: Cobalamin]]
[[Category: Exporter fold]]
[[Category: Import]]
[[Category: Transport protein]]
[[Category: Tuberculosis]]
[[Category: Vitamin b12]]
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