5f08: Difference between revisions
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<StructureSection load='5f08' size='340' side='right'caption='[[5f08]], [[Resolution|resolution]] 1.92Å' scene=''> | <StructureSection load='5f08' size='340' side='right'caption='[[5f08]], [[Resolution|resolution]] 1.92Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5f08]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F08 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5f08]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_CDC1551 Mycobacterium tuberculosis CDC1551]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F08 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5TG:~{TERT}-BUTYL+~{N}-METHYL-~{N}-[[4-[4-(3-OXIDANYLIDENE-3-PYRROLIDIN-1-YL-PROPYL)PIPERIDIN-1-YL]PHENYL]METHYL]CARBAMATE'>5TG</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5TG:~{TERT}-BUTYL+~{N}-METHYL-~{N}-[[4-[4-(3-OXIDANYLIDENE-3-PYRROLIDIN-1-YL-PROPYL)PIPERIDIN-1-YL]PHENYL]METHYL]CARBAMATE'>5TG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f08 OCA], [https://pdbe.org/5f08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f08 RCSB], [https://www.ebi.ac.uk/pdbsum/5f08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f08 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Complement C3 3D structures|Complement C3 3D structures]] | *[[Complement C3 3D structures|Complement C3 3D structures]] | ||
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Abell | [[Category: Mycobacterium tuberculosis CDC1551]] | ||
[[Category: Blaszczyk | [[Category: Abell C]] | ||
[[Category: Blundell | [[Category: Blaszczyk M]] | ||
[[Category: Nikiforov | [[Category: Blundell TL]] | ||
[[Category: Surade | [[Category: Nikiforov PO]] | ||
[[Category: Surade S]] | |||
Latest revision as of 08:37, 12 July 2023
Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium tuberculosis in complex with compound 14 at 1.92A resolution
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