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| | ==3D structures of general secretion pathway protein== |
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| ==3D structures of general secretion pathway protein== | | ==3D structures of general secretion pathway protein== |
| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} |
Revision as of 08:54, 2 August 2020
| Status: waiting for Mol* initialization | |
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Function
General secretion pathway proteins (Eps) are used by gram-negative pathogenic bacteria to transport their virulence factors outside of the cell via type II secretion system or T2SS. Examples are the transport of cholera toxin by Vibrio cholerae and exotoxin A by Pseudomonas aeruginosa[1]. In Pseudomonas aeruginosa the Eps are named Xcp. EpsG,H,I,J,K are named PulG, PulH, PulI, PulJ, PulK. See Pseudopilin.
Structural highlights
The 3D structure of the bacterial core shows a 15-fold rotationally symmetric PulD called secretin which inserts into the cell membrane and enables conductance of substrate intothe external environment[2].
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3D structures of general secretion pathway protein
General secretion pathway protein 3D structures
3D structures of general secretion pathway protein
Updated on 02-August-2020
{"openlevels":0}
- General secretion pathway protein AB
- Pseudopilin - VvEpsD residues 326-584 - Vibrio vulnificus
- General secretion pathway protein B
- 4wfw - DdEpsB residues 112-201 - Dickeya dadantii
- General secretion pathway protein C
- 2i4s, 2i6v - VcEpsC PDZ domain 204-305 - Vibrio cholerae
- 2lnv - DdEpsC residues 77-172
- General secretion pathway protein C+D+S
- 6hcg - KpEpsC + EpsD + EpsS - Klebsiella pneumoniae - Cryo EM
- General secretion pathway protein D
- 6i1y - VvEpsD residues 121-673 - Cryo EM
- 3ezj - EpsD N-terminal 40-277 + nanobody - Eschericia coli
- 4e9j - PaEpsD N-terminal 35-277 - Pseudomonas aeruginosa
- 4ec5 - PaEpsD N-terminal (mutant)
- 5wln - PaEpsD residues 35-658 - Cryo EM
- 6i1x - EpsD residues 122-645 - Aeromonas hydrophila - Cryo EM
- General secretion pathway protein E
- General secretion pathway protein E+L
- 2bh1 - VcEpsE residues 1-96 + VcEpsL residues 5-246
- General secretion pathway protein F
- General secretion pathway protein L
- 1yf5, 1w97 - VcEpsL cytoplasmic domain 1-248
- 2w7v - EpsL periplasmic domain 319-404 - Vibrio parahaemolyticus
- 5n7l - PaEpsL periplasmic domain 303-382
- 5hl8 - KpEpsL C-terminal domain 309-397
- General secretion pathway protein M
- 1uv7 - VcEpsM periplasmic domain 65-165
- General secretion pathway protein G,H,I,J,K see Pseudopilin
References
