6otl: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
Line 3: Line 3:
<StructureSection load='6otl' size='340' side='right'caption='[[6otl]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
<StructureSection load='6otl' size='340' side='right'caption='[[6otl]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6otl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aedae Aedae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OTL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6OTL FirstGlance]. <br>
<table><tr><td colspan='2'>[[6otl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aedes_aegypti Aedes aegypti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OTL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OTL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TBR:HEXATANTALUM+DODECABROMIDE'>TBR</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6og0|6og0]], [[6ogh|6ogh]], [[6oii|6oii]], [[6omw|6omw]], [[6opb|6opb]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">5567053, AAEL005772 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7159 AEDAE])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6otl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6otl OCA], [https://pdbe.org/6otl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6otl RCSB], [https://www.ebi.ac.uk/pdbsum/6otl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6otl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6otl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6otl OCA], [http://pdbe.org/6otl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6otl RCSB], [http://www.ebi.ac.uk/pdbsum/6otl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6otl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OBP22_AEDAE OBP22_AEDAE] Involved in modulation of blood-feeding behavior and capacity in female mosquitoes (PubMed:22479185, PubMed:34634943). Required for normal oviposition (PubMed:34634943). Required for normal fecundity and fertility of female and male mosquitoes (PubMed:34634943). Required for normal expression of VGA1 gene, which encodes the egg yolk protein vitellogenin-A1 (PubMed:34634943). Involved in regulation of spermatozoa development (PubMed:34634943). Required for normal female longevity when mosquitoes are maintained on regular sugar meal (PubMed:34634943). Binds long chain fatty acids (PubMed:32094450).<ref>PMID:22479185</ref> <ref>PMID:32094450</ref> <ref>PMID:34634943</ref>  (Microbial infection) Facilitates shedding of dengue virus type 2 particles into mosquito saliva (PubMed:34634943). Does not affect dengue virus type 2 replication or infection prevalence in midgut and salivary glands at 14 days after blood feeding (PubMed:34634943).<ref>PMID:34634943</ref>  (Microbial infection) Facilitates shedding of Zika virus particles into mosquito saliva (PubMed:34634943). Does not affect Zika virus replication or infection prevalence in midgut and salivary glands at 14 days after blood feeding (PubMed:34634943).<ref>PMID:34634943</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 25: Line 26:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aedae]]
[[Category: Aedes aegypti]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Jones, D N]]
[[Category: Jones DN]]
[[Category: Murphy, E]]
[[Category: Murphy E]]
[[Category: Chemo-sensory signaling]]
[[Category: Odorant-binding protein]]
[[Category: Transport protein]]
Retrieved from "https://proteopedia.org/6otl"