Sandbox Reserved 896: Difference between revisions

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[[Image:BRD2BD1SurfaceView.png]]
[[Image:BRD2BD1SurfaceView.png]]


Figure 1: Surface view of BD1 homo-2-mer binding N-acetyl-lysine 12 of histone H4. The hypoacetylated side chain of lysine 8 that coordinates the dimer interface cannot be seen in this figure. Figure produced by PyMol (PDB ID: 2DVQ).
Figure 1: Surface view of BD1 binding N-acetyl-lysine 12 of histone H4. The hypoacetylated side chain of lysine 8 that coordinates the dimer interface cannot be seen in this figure. Figure produced by PyMol (PDB ID: 2DVQ).


== Structure ==
== Structure ==
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[[Image:BD1HomodimerTertiaryStructure.png]]  
[[Image:BD1HomodimerTertiaryStructure.png]]  


Figure 2: Tertiary Structure of BRD2-BD1 homodimer in complex with N-acetyl-lysine 12 of histone H4. Figure produced by PyMol (PDB ID: 2DVQ)
Figure 2: Tertiary Structure of BRD2-BD1 in complex with N-acetyl-lysine 12 of histone H4. Figure produced by PyMol (PDB ID: 2DVQ)
== Medical Relevance ==
== Medical Relevance ==