6s4m: Difference between revisions
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==Crystal structure of the human organic anion transporter MFSD10 (TETRAN)== | ==Crystal structure of the human organic anion transporter MFSD10 (TETRAN)== | ||
<StructureSection load='6s4m' size='340' side='right'caption='[[6s4m]]' scene=''> | <StructureSection load='6s4m' size='340' side='right'caption='[[6s4m]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S4M OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6s4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6S4M FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MFSD10, TETRAN ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6s4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s4m OCA], [https://pdbe.org/6s4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6s4m RCSB], [https://www.ebi.ac.uk/pdbsum/6s4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6s4m ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/MFS10_HUMAN MFS10_HUMAN]] Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump.<ref>PMID:17362938</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra C]] | [[Category: Bountra, C]] | ||
[[Category: Burgess-Brown | [[Category: Burgess-Brown, N A]] | ||
[[Category: Bushell | [[Category: Bushell, S R]] | ||
[[Category: Carpenter | [[Category: Carpenter, E P]] | ||
[[Category: Chalk R]] | [[Category: Chalk, R]] | ||
[[Category: Chu A]] | [[Category: Chu, A]] | ||
[[Category: Edwards | [[Category: Edwards, A M]] | ||
[[Category: Mukhopadhyay | [[Category: Mukhopadhyay, S M.M]] | ||
[[Category: Pascoa | [[Category: Pascoa, T C]] | ||
[[Category: Pike | [[Category: Pike, A C.W]] | ||
[[Category: Quigley A]] | [[Category: Quigley, A]] | ||
[[Category: Shrestha L]] | [[Category: Structural genomic]] | ||
[[Category: Venkaya S]] | [[Category: Shrestha, L]] | ||
[[Category: Venkaya, S]] | |||
[[Category: Amtf1]] | |||
[[Category: Membrane transporter]] | |||
[[Category: Mfsd10]] | |||
[[Category: Sgc]] | |||
[[Category: Slc22a32]] | |||
[[Category: Tetran]] | |||
[[Category: Transport protein]] | |||
Revision as of 09:58, 14 July 2021
Crystal structure of the human organic anion transporter MFSD10 (TETRAN)
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