Nerve growth factor: Difference between revisions
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<StructureSection load='2ifg' size='340' side='right' caption=' | <StructureSection load='2ifg' size='340' side='right' caption='Human NGF (pink, yellow) complex with glycosylated TrkA receptor (grey, green) )PDB code [[2ifg]])' scene=''> | ||
== Function == | == Function == | ||
'''Nerve growth factor''' (NGF) belongs to the family of neurotrophins. NGF promotes survival and differentiation of sensory and sympathetic neurons. NGF signaling furthers neuroprotective and repair functions<ref>PMID:11520933</ref>. | '''Nerve growth factor''' (NGF) belongs to the family of neurotrophins. NGF promotes survival and differentiation of sensory and sympathetic neurons. NGF signaling furthers neuroprotective and repair functions<ref>PMID:11520933</ref>. NGF interacts with 2 transmembrane receptors - TrkA and p75. | ||
== Relevance == | == Relevance == | ||