6k26: Difference between revisions
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==Crystal structure of Vibrio cholerae methionine aminopeptidase== | ==Crystal structure of Vibrio cholerae methionine aminopeptidase== | ||
<StructureSection load='6k26' size='340' side='right'caption='[[6k26]]' scene=''> | <StructureSection load='6k26' size='340' side='right'caption='[[6k26]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K26 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6K26 FirstGlance]. <br> | <table><tr><td colspan='2'>[[6k26]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillo_virgola_del_koch"_trevisan_1884 "bacillo virgola del koch" trevisan 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K26 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6K26 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6k26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k26 OCA], [http://pdbe.org/6k26 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6k26 RCSB], [http://www.ebi.ac.uk/pdbsum/6k26 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6k26 ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">map ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 "Bacillo virgola del Koch" Trevisan 1884])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6k26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k26 OCA], [http://pdbe.org/6k26 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6k26 RCSB], [http://www.ebi.ac.uk/pdbsum/6k26 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6k26 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/A0A085RSZ7_VIBCL A0A085RSZ7_VIBCL]] Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.[ARBA:ARBA00002521][HAMAP-Rule:MF_01974] | |||
==See Also== | |||
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bacillo virgola del koch trevisan 1884]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Addlagatta A]] | [[Category: Methionyl aminopeptidase]] | ||
[[Category: Pillalamarri V]] | [[Category: Addlagatta, A]] | ||
[[Category: Pillalamarri, V]] | |||
[[Category: Hydrolase]] | |||
[[Category: Metap]] | |||
[[Category: Methionine aminopeptidase]] | |||
