5hfs: Difference between revisions

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<StructureSection load='5hfs' size='340' side='right'caption='[[5hfs]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
<StructureSection load='5hfs' size='340' side='right'caption='[[5hfs]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5hfs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_33277 Atcc 33277]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HFS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HFS FirstGlance]. <br>
<table><tr><td colspan='2'>[[5hfs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Porphyromonas_gingivalis Porphyromonas gingivalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HFS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HFS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rgpB, prtRII, rgp2, PG_0506 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=837 ATCC 33277])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Gingipain_R Gingipain R], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.37 3.4.22.37] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hfs OCA], [https://pdbe.org/5hfs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hfs RCSB], [https://www.ebi.ac.uk/pdbsum/5hfs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hfs ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hfs OCA], [http://pdbe.org/5hfs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hfs RCSB], [http://www.ebi.ac.uk/pdbsum/5hfs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hfs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CPG2_PORGI CPG2_PORGI]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Its proteolytic activity is a major factor in both periodontal tissue destruction and in bacterial host defense mechanisms. Activates complement C3 and C5 (By similarity).  
[https://www.uniprot.org/uniprot/CPG2_PORGI CPG2_PORGI] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Its proteolytic activity is a major factor in both periodontal tissue destruction and in bacterial host defense mechanisms. Activates complement C3 and C5 (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 33277]]
[[Category: Gingipain R]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Dubin, G]]
[[Category: Porphyromonas gingivalis]]
[[Category: Golik, P]]
[[Category: Dubin G]]
[[Category: Ksiazek, M]]
[[Category: Golik P]]
[[Category: Mizgalska, D]]
[[Category: Ksiazek M]]
[[Category: Nowak, M]]
[[Category: Mizgalska D]]
[[Category: Nowakowska, Z]]
[[Category: Nowak M]]
[[Category: Potempa, J]]
[[Category: Nowakowska Z]]
[[Category: Szmigielski, B]]
[[Category: Potempa J]]
[[Category: Hydrolase]]
[[Category: Szmigielski B]]
[[Category: Ig-like domain]]
[[Category: Protease]]
[[Category: Type ix secretion system]]
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