Sandbox Reserved 1095: Difference between revisions

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Angiotensin Receptor Blockers (ARBs) are used to cure diseases linked to AT1R.

The ARB [https://en.wikipedia.org/wiki/Olmesartan olmesartan] is anchored to ATR1 by the residues <scene name='82/829348/Tyr35/6'>Tyr35</scene>, <scene name='82/829348/Trp84/5'>Trp84</scene> and <scene name='82/829348/Arg167/3'>Arg167</scene>.

<scene name='82/829348/3_residues_bound_to_ligand/1'>Those three amino acids</scene> seem to play an important role in the binding of the drug to AT1R, thanks to the formation of extensive networks of hydrogen bonds and salt bridges with the ligand <ref name="Zhang2015"/>.

<scene name='82/829348/3_residues_bound_to_ligand/2'>Those three amino acids</scene> seem to play an important role in the binding of the drug to AT1R, thanks to the formation of extensive networks of hydrogen bonds and salt bridges with the ligand <ref name="Zhang2015"/>.

Many ARBs contain a [https://en.wikipedia.org/wiki/Tetrazole tetrazole] group. Studies showed that tetrazole plays an important role in the binding with AT1R.

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@@ Line 40: / Line 40: @@
 Angiotensin Receptor Blockers (ARBs) are used to cure diseases linked to AT1R.
 The ARB [https://en.wikipedia.org/wiki/Olmesartan olmesartan] is anchored to ATR1 by the residues <scene name='82/829348/Tyr35/6'>Tyr35</scene>, <scene name='82/829348/Trp84/5'>Trp84</scene> and <scene name='82/829348/Arg167/3'>Arg167</scene>.
-<scene name='82/829348/3_residues_bound_to_ligand/1'>Those three amino acids</scene> seem to play an important role in the binding of the drug to AT1R, thanks to the formation of extensive networks of hydrogen bonds and salt bridges with the ligand <ref name="Zhang2015"/>.
+<scene name='82/829348/3_residues_bound_to_ligand/2'>Those three amino acids</scene> seem to play an important role in the binding of the drug to AT1R, thanks to the formation of extensive networks of hydrogen bonds and salt bridges with the ligand <ref name="Zhang2015"/>.
 Many ARBs contain a [https://en.wikipedia.org/wiki/Tetrazole tetrazole] group. Studies showed that tetrazole plays an important role in the binding with AT1R.