6kbm: Difference between revisions

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<StructureSection load='6kbm' size='340' side='right'caption='[[6kbm]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='6kbm' size='340' side='right'caption='[[6kbm]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6kbm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KBM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6KBM FirstGlance]. <br>
<table><tr><td colspan='2'>[[6kbm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KBM FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6kbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kbm OCA], [http://pdbe.org/6kbm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kbm RCSB], [http://www.ebi.ac.uk/pdbsum/6kbm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kbm ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.902&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kbm OCA], [https://pdbe.org/6kbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kbm RCSB], [https://www.ebi.ac.uk/pdbsum/6kbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kbm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VAC8_YEAST VAC8_YEAST]] Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.<ref>PMID:9490720</ref> [[http://www.uniprot.org/uniprot/ATG13_YEAST ATG13_YEAST]] Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy. Required for autophosphorylation of ATG1 at 'Thr-226' and its dimerization. May also be involved in the regulation of autophagy through SNF1. Involved in ATG9 and ATG23 cycling through the pre-autophagosomal structure. Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation. Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy. Finally, ATG13 is also required for glycogen storage during stationary phase.<ref>PMID:10837477</ref> <ref>PMID:10995454</ref> <ref>PMID:11086004</ref> <ref>PMID:11486014</ref> <ref>PMID:14723849</ref> <ref>PMID:15743910</ref> <ref>PMID:17295840</ref> <ref>PMID:17426440</ref> <ref>PMID:17699586</ref> <ref>PMID:18077553</ref> <ref>PMID:18287526</ref> <ref>PMID:19805182</ref> <ref>PMID:19995911</ref> <ref>PMID:20439775</ref> <ref>PMID:20647741</ref> <ref>PMID:20855505</ref> <ref>PMID:21468027</ref> <ref>PMID:21712380</ref> <ref>PMID:22447937</ref> <ref>PMID:22778255</ref> <ref>PMID:22782902</ref> <ref>PMID:22885598</ref> <ref>PMID:8224160</ref> 
[https://www.uniprot.org/uniprot/VAC8_YEAST VAC8_YEAST] Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.<ref>PMID:9490720</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6kbm" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6kbm" style="background-color:#fffaf0;"></div>
==See Also==
*[[Autophagy-related protein 3D structures|Autophagy-related protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lee, C]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Park, J]]
[[Category: Lee C]]
[[Category: Armadillo repeat]]
[[Category: Park J]]
[[Category: Complex]]
[[Category: Protein binding-protein transport complex]]
Retrieved from "https://proteopedia.org/6kbm"