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==NMR Structures Show Unwinding of the GCN4p Coiled Coil Superhelix Accompanying Disruption of Ion Pairs at Acidic pH==
==NMR Structures Show Unwinding of the GCN4p Coiled Coil Superhelix Accompanying Disruption of Ion Pairs at Acidic pH==
<StructureSection load='5iir' size='340' side='right'caption='[[5iir]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='5iir' size='340' side='right'caption='[[5iir]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5iir]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IIR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IIR FirstGlance]. <br>
<table><tr><td colspan='2'>[[5iir]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IIR FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5iiv|5iiv]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GCN4, AAS3, ARG9, YEL009C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iir OCA], [https://pdbe.org/5iir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iir RCSB], [https://www.ebi.ac.uk/pdbsum/5iir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iir ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5iir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iir OCA], [http://pdbe.org/5iir PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iir RCSB], [http://www.ebi.ac.uk/pdbsum/5iir PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iir ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST]] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.  
[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Gcn4 3D Structures|Gcn4 3D Structures]]
*[[Gnc4 3D Structures|Gnc4 3D Structures]]
*[[Gnc4 3D Structures|Gnc4 3D Structures]]
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Alexandrescu, A T]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Brady, M R]]
[[Category: Alexandrescu AT]]
[[Category: Kaplan, A R]]
[[Category: Brady MR]]
[[Category: Canonical alpha helix]]
[[Category: Kaplan AR]]
[[Category: Closely related nmr structure]]
[[Category: Conformational transition]]
[[Category: Electrostatic]]
[[Category: Knobs-into-hole]]
[[Category: Leucine zipper]]
[[Category: Salt bridge]]
[[Category: Supercoil parameter]]
[[Category: Transcription]]
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