6qv8: Difference between revisions

<table><tr><td colspan='2'>[[6qv8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QV8 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qv8 OCA], [https://pdbe.org/6qv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qv8 RCSB], [https://www.ebi.ac.uk/pdbsum/6qv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qv8 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SODM2_STAA8 SODM2_STAA8] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site. May play a role in maintaining cell viability during the late-exponential and stationary phases of growth since it becomes a major source of activity under oxidative stress. Has a role in resisting external superoxide stress. Involved in acid tolerance and the acid-adaptive response. Mediates the derepression of perR regulon in the response to HOCl stress at low level of SOD activity (By similarity).<ref>PMID:11344148</ref> <ref>PMID:14523108</ref>