5j4k: Difference between revisions

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<StructureSection load='5j4k' size='340' side='right'caption='[[5j4k]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
<StructureSection load='5j4k' size='340' side='right'caption='[[5j4k]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5j4k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J4K OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5J4K FirstGlance]. <br>
<table><tr><td colspan='2'>[[5j4k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J4K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J4K FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6FZ:2,3-DIHYDRO-1H-INDENE-2-CARBOXYLIC+ACID'>6FZ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6FZ:2,3-DIHYDRO-1H-INDENE-2-CARBOXYLIC+ACID'>6FZ</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">radA, PF1926 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j4k OCA], [https://pdbe.org/5j4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j4k RCSB], [https://www.ebi.ac.uk/pdbsum/5j4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j4k ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5j4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j4k OCA], [http://pdbe.org/5j4k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5j4k RCSB], [http://www.ebi.ac.uk/pdbsum/5j4k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5j4k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.  
[https://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pyrfu]]
[[Category: Pyrococcus furiosus DSM 3638]]
[[Category: Abell, C]]
[[Category: Abell C]]
[[Category: Blundell, T L]]
[[Category: Blundell TL]]
[[Category: Fischer, G]]
[[Category: Fischer G]]
[[Category: Hyvonen, M]]
[[Category: Hyvonen M]]
[[Category: Marsh, M]]
[[Category: Marsh M]]
[[Category: Morgan, M]]
[[Category: Morgan M]]
[[Category: Moschetti, T]]
[[Category: Moschetti T]]
[[Category: Ng, H]]
[[Category: Ng H]]
[[Category: Scott, D]]
[[Category: Scott D]]
[[Category: Sharpe, T]]
[[Category: Sharpe T]]
[[Category: Skidmore, J]]
[[Category: Skidmore J]]
[[Category: Venkitaraman, A]]
[[Category: Venkitaraman A]]
[[Category: Dna repair]]
[[Category: Fragment based drug design]]
[[Category: Humanisation]]
[[Category: Hydrolase]]
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