1bj7: Difference between revisions

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[[Image:1bj7.gif|left|200px]]
{{Seed}}
[[Image:1bj7.png|left|200px]]


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{{STRUCTURE_1bj7|  PDB=1bj7  |  SCENE=  }}  
{{STRUCTURE_1bj7|  PDB=1bj7  |  SCENE=  }}  


'''BOVINE LIPOCALIN ALLERGEN BOS D 2'''
===BOVINE LIPOCALIN ALLERGEN BOS D 2===




==Overview==
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The three-dimensional structure of the major bovine allergen Bos d 2 has been determined by using x-ray diffraction at 1.8-A resolution. Structurally Bos d 2 is a member of the lipocalin family comprising proteins with transport functions. There is a flat small cavity inside the Bos d 2 protein core suitable for ligand binding, and it is possible that Glu115 and Asn37 inside the core are able to make hydrogen bonds with the ligand. Many allergens from different animals belong to the lipocalin family. The amino acid residue similarities between these lipocalins indicate putative regions for IgE binding. Comparison with the available allergen structures from other sources suggests that these allergens are roughly the same size and that their shape is more spherical than elliptical.
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{{ABSTRACT_PUBMED_9891000}}


==About this Structure==
==About this Structure==
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[[Category: Allergen]]
[[Category: Allergen]]
[[Category: Lipocalin]]
[[Category: Lipocalin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 11:35:05 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:15:11 2008''

Revision as of 16:15, 30 June 2008

File:1bj7.png

Template:STRUCTURE 1bj7

BOVINE LIPOCALIN ALLERGEN BOS D 2

Template:ABSTRACT PUBMED 9891000

About this Structure

1BJ7 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Probing the molecular basis of allergy. three-dimensional structure of the bovine lipocalin allergen Bos d 2., Rouvinen J, Rautiainen J, Virtanen T, Zeiler T, Kauppinen J, Taivainen A, Mantyjarvi R, J Biol Chem. 1999 Jan 22;274(4):2337-43. PMID:9891000

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