2vbc: Difference between revisions

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<StructureSection load='2vbc' size='340' side='right'caption='[[2vbc]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
<StructureSection load='2vbc' size='340' side='right'caption='[[2vbc]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2vbc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_4 Dengue virus 4]. The July 2008 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Dengue Virus''  by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2008_7 10.2210/rcsb_pdb/mom_2008_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VBC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2vbc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_4 Dengue virus 4]. The July 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Dengue Virus''  by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_7 10.2210/rcsb_pdb/mom_2008_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VBC FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbc OCA], [http://pdbe.org/2vbc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vbc RCSB], [http://www.ebi.ac.uk/pdbsum/2vbc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vbc ProSAT]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vbc OCA], [https://pdbe.org/2vbc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vbc RCSB], [https://www.ebi.ac.uk/pdbsum/2vbc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vbc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q2TN89_9FLAV Q2TN89_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]  
[[https://www.uniprot.org/uniprot/Q2TN89_9FLAV Q2TN89_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Helicase 3D structures|Helicase 3D structures]]
*[[Helicase 3D structures|Helicase 3D structures]]
*[[Virus proteases 3D strutures|Virus proteases 3D strutures]]
*[[Virus protease 3D structures|Virus protease 3D structures]]
== References ==
== References ==
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<references/>