2wbl: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
<StructureSection load='2wbl' size='340' side='right'caption='[[2wbl]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='2wbl' size='340' side='right'caption='[[2wbl]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wbl]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2wbl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WBL FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbl OCA], [https://pdbe.org/2wbl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wbl RCSB], [https://www.ebi.ac.uk/pdbsum/2wbl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbl ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/ROGF8_ARATH ROGF8_ARATH]] Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. Active as homodimer.<ref>PMID:17218277</ref> [[https://www.uniprot.org/uniprot/RAC2_ARATH RAC2_ARATH]] Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||