7c4i: Difference between revisions

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==High resolution structure of BRPF1 bromodomain==
==High resolution structure of BRPF1 Bromo Domain from Biortus==
<StructureSection load='7c4i' size='340' side='right'caption='[[7c4i]]' scene=''>
<StructureSection load='7c4i' size='340' side='right'caption='[[7c4i]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C4I OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7C4I FirstGlance]. <br>
<table><tr><td colspan='2'>[[7c4i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C4I FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7c4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c4i OCA], [http://pdbe.org/7c4i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7c4i RCSB], [http://www.ebi.ac.uk/pdbsum/7c4i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7c4i ProSAT]</span></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRPF1, BR140 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c4i OCA], [https://pdbe.org/7c4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c4i RCSB], [https://www.ebi.ac.uk/pdbsum/7c4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c4i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref> 
==See Also==
*[[Peregrin|Peregrin]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lin D]]
[[Category: Lin, D]]
[[Category: Lv Z]]
[[Category: Lv, Z]]
[[Category: Wang F]]
[[Category: Wang, F]]
[[Category: Zhu B]]
[[Category: Zhu, B]]
[[Category: Dna binding protein]]

Revision as of 07:31, 9 February 2022

High resolution structure of BRPF1 Bromo Domain from Biortus

7c4i, resolution 1.37Å

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