Factor XIa: Difference between revisions
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*Factor XIa | *Factor XIa | ||
**[[2j8j]], [[2j8l]] – hFXIa A4 domain (residues 290-379) – human – NMR<br /> | **[[2j8j]], [[2j8l]] – hFXIa A4 domain (residues 290-379) – human – NMR<br /> | ||
**[[2f83]] - hFXIa zymogen (residues 1-625) | **[[2f83]], [[6i58]] - hFXIa zymogen (residues 1-625) | ||
*Factor XIa light chain catalytic domain (residues 388-625) inhibitor complex | *Factor XIa light chain catalytic domain (residues 388-625) inhibitor complex | ||
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**[[4na7]], [[4na8]], [[4y8x]], [[6usy]] - hFXIa + inhibitor<br /> | **[[4na7]], [[4na8]], [[4y8x]], [[6usy]] - hFXIa + inhibitor<br /> | ||
**[[4y8z]], [[6vlu]] - hFXIa + quinoline inhibitor<br /> | **[[4y8z]], [[6vlu]] - hFXIa + quinoline inhibitor<br /> | ||
**[[5e2o]], [[5exm]], [[5tkt]] - hFXIa (mutant) + inhibitor<br /> | **[[5e2o]], [[5exm]], [[5tkt]], [[6ts4]], [[6ts5]], [[6ts6]] - hFXIa (mutant) + inhibitor<br /> | ||
**[[4cr5]], [[4cr9]], [[4cra]], [[4crb]], [[4cre]], [[4crf]], [[1ztl]], [[4ty7]], [[4wxi]], [[4d76]], [[4d7f]], [[4d7g]], [[5e2p]], [[6vlv]] - hFXIa (mutant) + quinolin inhibitor<br /> | **[[4cr5]], [[4cr9]], [[4cra]], [[4crb]], [[4cre]], [[4crf]], [[1ztl]], [[4ty7]], [[4wxi]], [[4d76]], [[4d7f]], [[4d7g]], [[5e2p]], [[6ts7]], [[6vlv]] - hFXIa (mutant) + quinolin inhibitor<br /> | ||
**[[4y8y]] - hFXIa + tetrazol inhibitor<br /> | **[[4y8y]] - hFXIa + tetrazol inhibitor<br /> | ||
**[[4crc]], [[4crd]], [[3sor]], [[1zpc]], [[3sos]], [[4x6o]], [[5exn]], [[5tku]] - hFXIa (mutant) + tetrazol inhibitor<br /> | **[[4crc]], [[4crd]], [[3sor]], [[1zpc]], [[3sos]], [[4x6o]], [[5exn]], [[5tku]], [[6c0s]] - hFXIa (mutant) + tetrazol inhibitor<br /> | ||
**[[ | **[[6w50]] - hFXIa + pyrimidine inhibitor<br /> | ||
**[[1ztk]], [[1ztj]], [[1zsl]] - hFXIa (mutant) + | **[[1ztk]], [[1ztj]], [[1zsl]], [[4crg]] - hFXIa (mutant) + pyrimidine inhibitor<br /> | ||
**[[4x6m]], [[4x6p]], [[5exl]] - hFXIa (mutant) + indazole inhibitor<br /> | **[[4x6m]], [[4x6p]], [[5exl]] - hFXIa (mutant) + indazole inhibitor<br /> | ||
**[[4x6n]] - hFXIa (mutant) + indazole inhibitor + peptide<br /> | **[[4x6n]] - hFXIa (mutant) + indazole inhibitor + peptide<br /> | ||
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**[[1xxd]], [[1xxf]] - hFXIa (mutant) + ecotin (mutant)<br /> | **[[1xxd]], [[1xxf]] - hFXIa (mutant) + ecotin (mutant)<br /> | ||
**[[4ty6]] - hFXIa light chain (mutant) + heavy chain peptide + benzamine inhibitor<br /> | **[[4ty6]] - hFXIa light chain (mutant) + heavy chain peptide + benzamine inhibitor<br /> | ||
**[[6r8x]] - hFXIa light chain + antibody<br /> | |||
**[[6aod]], [[6hhc]] - hFXIa light chain (mutant) + antibody<br /> | |||
**[[6twb]], [[6twc]] - hFXIa light chain + peptide<br /> | |||
}} | }} | ||
==References== | ==References== | ||
