Sandbox 20005: Difference between revisions

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Joel L. Sussman (talk | contribs)
ConfirmAccount, Editor, Mutation, Print3D, Tester, Bureaucrats, journal
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Joel L. Sussman (talk | contribs)
ConfirmAccount, Editor, Mutation, Print3D, Tester, Bureaucrats, journal
11,629 edits
No edit summary
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<StructureSection load='' size='300' side='right' caption='Morph showing the transition of SARS-CoV-2 spike protein from its closed to open conformation induced by proteolytic cleavage by furin, see [[http://proteopedia.org/wiki/index.php/SARS-CoV-2_protein_S_activation_by_furin Details of this morph]]' scene='85/857125/Morph_alpha_carbons_only/7'>
<StructureSection load='' size='300' side='right' caption='Morph showing the transition of SARS-CoV-2 spike protein from its closed to open conformation induced by proteolytic cleavage by furin, see [[http://proteopedia.org/wiki/index.php/SARS-CoV-2_protein_S_activation_by_furin Details of this morph]]' scene='85/857125/Morph_alpha_carbons_only/7'>


<scene name='85/857141/Morph_alpha_carbons_only/1'>yyy_new</scene>
 


[[Image:Ezgif.com-video-to-gif 240px 65pc speed.gif|left|240px|thumb|<span style="font-size:100%">SARS-CoV-2 virus. The <span style="color:blue">spikes</span>, that adorn the <span style="color:red">'''virus surface'''</span>, impart a '''''corona''''' like appearance [http://www.drugtargetreview.com/news/57287/3d-visualisation-of-covid-19-surface-released-for-researchers (Fusion Animation)].</span>]]
[[Image:Ezgif.com-video-to-gif 240px 65pc speed.gif|left|240px|thumb|<span style="font-size:100%">SARS-CoV-2 virus. The <span style="color:blue">spikes</span>, that adorn the <span style="color:red">'''virus surface'''</span>, impart a '''''corona''''' like appearance [http://www.drugtargetreview.com/news/57287/3d-visualisation-of-covid-19-surface-released-for-researchers (Fusion Animation)].</span>]]
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A [http://youtu.be/hwVl_-lnoys '''''video'''''] (by [http://elarasystems.com Elara)] shows how the virus [http://youtu.be/hwVl_-lnoys '''interacts with its human (host) cells'''], via its ''spikes'' (3D structure determined in the McLellan Lab (U of Texas, Austin)<ref name="McLellan">PMID:32075877</ref>)) and  Wrobel, Benton & Gamblin labs <ref name="wrobel">PMID: 32647346</ref> (Crick Institute, London), thus permitting the viral genome to enter its host & begin infection.  The spike protein is induced for optimal binding when it is clipped by a protease (see animation on right side) and [[SARS-CoV-2 protein S priming by furin|'''more information''']].
A [http://youtu.be/hwVl_-lnoys '''''video'''''] (by [http://elarasystems.com Elara)] shows how the virus [http://youtu.be/hwVl_-lnoys '''interacts with its human (host) cells'''], via its ''spikes'' (3D structure determined in the McLellan Lab (U of Texas, Austin)<ref name="McLellan">PMID:32075877</ref>)) and  Wrobel, Benton & Gamblin labs <ref name="wrobel">PMID: 32647346</ref> (Crick Institute, London), thus permitting the viral genome to enter its host & begin infection.  The spike protein is induced for optimal binding when it is clipped by a protease (see animation on right side) and [[SARS-CoV-2 protein S priming by furin|'''more information''']].
</span>
</span>
<scene name='85/857141/Morph_alpha_carbons_only/1'>yyy_new</scene>




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