2zhp: Difference between revisions

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<StructureSection load='2zhp' size='340' side='right'caption='[[2zhp]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='2zhp' size='340' side='right'caption='[[2zhp]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zhp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptoalloteichus_hindustanus"_tomita_et_al._1978 "streptoalloteichus hindustanus" tomita et al. 1978]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZHP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2ZHP FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zhp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptoalloteichus_hindustanus Streptoalloteichus hindustanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZHP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BY6:[(2S,3R,4R,5S,6S)-2-[(3R,4R,5R,6R)-2-[(1R,2S)-2-[[6-AMINO-2-[(1S)-3-AMINO-1-[(2,3-DIAMINO-3-OXOPROPYL)AMINO]-3-OXOPROPYL]-5-METHYLPYRIMIDINE-4-CARBONYL]AMINO]-3-[[(2S,3R,4R)-5-[[(2R,3S)-1-[2-[4-[4-[3-[4-(3-AMINOPROPYLAMINO)BUTYLAMINO]PROPYLCARBAMOYL]-1,3-THIAZOL-2-YL]-1,3-THIAZOL-2-YL]ETHYLAMINO]-3-HYDROXY-1-OXOBUTAN-2-YL]AMINO]-3-HYDROXY-4-METHYL-5-OXOPENTAN-2-YL]AMINO]-1-(3H-IMIDAZOL-4-YL)-3-OXOPROPOXY]-4,5-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-3-YL]OXY-3,5-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-4-YL]+CARBAMATE'>BY6</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1byl|1byl]], [[1xrk|1xrk]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BY6:[(2S,3R,4R,5S,6S)-2-[(3R,4R,5R,6R)-2-[(1R,2S)-2-[[6-AMINO-2-[(1S)-3-AMINO-1-[(2,3-DIAMINO-3-OXOPROPYL)AMINO]-3-OXOPROPYL]-5-METHYLPYRIMIDINE-4-CARBONYL]AMINO]-3-[[(2S,3R,4R)-5-[[(2R,3S)-1-[2-[4-[4-[3-[4-(3-AMINOPROPYLAMINO)BUTYLAMINO]PROPYLCARBAMOYL]-1,3-THIAZOL-2-YL]-1,3-THIAZOL-2-YL]ETHYLAMINO]-3-HYDROXY-1-OXOBUTAN-2-YL]AMINO]-3-HYDROXY-4-METHYL-5-OXOPENTAN-2-YL]AMINO]-1-(3H-IMIDAZOL-4-YL)-3-OXOPROPOXY]-4,5-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-3-YL]OXY-3,5-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-4-YL]+CARBAMATE'>BY6</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2zhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zhp OCA], [http://pdbe.org/2zhp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zhp RCSB], [http://www.ebi.ac.uk/pdbsum/2zhp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zhp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zhp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zhp OCA], [https://pdbe.org/2zhp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zhp RCSB], [https://www.ebi.ac.uk/pdbsum/2zhp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zhp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BLE_STRHI BLE_STRHI]] Binding protein with a strong affinity to the bleomycin family of antibiotics.  
[https://www.uniprot.org/uniprot/BLE_STRHI BLE_STRHI] Binding protein with a strong affinity to the bleomycin family of antibiotics.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Streptoalloteichus hindustanus tomita et al. 1978]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Miyazaki, I]]
[[Category: Streptoalloteichus hindustanus]]
[[Category: Okumura, H]]
[[Category: Miyazaki I]]
[[Category: Osada, H]]
[[Category: Okumura H]]
[[Category: Simizu, S]]
[[Category: Osada H]]
[[Category: Antibiotic inhibitor]]
[[Category: Simizu S]]
[[Category: Antibiotic resistance]]
[[Category: Bleomycin]]
[[Category: Ligand binding protein]]
Retrieved from "https://proteopedia.org/2zhp"