2jis: Difference between revisions
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<StructureSection load='2jis' size='340' side='right'caption='[[2jis]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='2jis' size='340' side='right'caption='[[2jis]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jis]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2jis]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JIS FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jis OCA], [https://pdbe.org/2jis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jis RCSB], [https://www.ebi.ac.uk/pdbsum/2jis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jis ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CSAD_HUMAN CSAD_HUMAN] Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is 3-sulfino-L-alanine. Does not exhibit any decarboxylation activity toward glutamate.[UniProtKB:Q9DBE0] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2jis_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2jis_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith C]] | |||
[[Category: Arrowsmith | [[Category: Berglund H]] | ||
[[Category: Busam R]] | |||
[[Category: Berglund | [[Category: Collins R]] | ||
[[Category: Busam | [[Category: Dahlgren LG]] | ||
[[Category: Collins | [[Category: Edwards A]] | ||
[[Category: Dahlgren | [[Category: Flodin S]] | ||
[[Category: Edwards | [[Category: Flores A]] | ||
[[Category: Flodin | [[Category: Graslund S]] | ||
[[Category: Flores | [[Category: Hallberg BM]] | ||
[[Category: Graslund | [[Category: Hammarstrom M]] | ||
[[Category: Hallberg | [[Category: Holmberg-Schiavone L]] | ||
[[Category: Hammarstrom | [[Category: Johansson I]] | ||
[[Category: Holmberg-Schiavone | [[Category: Kallas A]] | ||
[[Category: Johansson | [[Category: Karlberg T]] | ||
[[Category: Kallas | [[Category: Kotenyova T]] | ||
[[Category: Karlberg | [[Category: Lehtio L]] | ||
[[Category: Kotenyova | [[Category: Moche M]] | ||
[[Category: Lehtio | [[Category: Nordlund P]] | ||
[[Category: Moche | [[Category: Nyman T]] | ||
[[Category: Nordlund | [[Category: Ogg D]] | ||
[[Category: Nyman | [[Category: Persson C]] | ||
[[Category: Ogg | [[Category: Sagemark J]] | ||
[[Category: Persson | [[Category: Stenmark P]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Sagemark | [[Category: Thorsell AG]] | ||
[[Category: Stenmark | [[Category: Tresaugues L]] | ||
[[Category: Sundstrom | [[Category: Weigelt J]] | ||
[[Category: Thorsell | [[Category: Welin M]] | ||
[[Category: Tresaugues | [[Category: Van den Berg S]] | ||
[[Category: Weigelt | |||
[[Category: Welin | |||
[[Category: | |||
Latest revision as of 08:28, 9 April 2025
Human cysteine sulfinic acid decarboxylase (CSAD) in complex with PLP.
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Large Structures
- Arrowsmith C
- Berglund H
- Busam R
- Collins R
- Dahlgren LG
- Edwards A
- Flodin S
- Flores A
- Graslund S
- Hallberg BM
- Hammarstrom M
- Holmberg-Schiavone L
- Johansson I
- Kallas A
- Karlberg T
- Kotenyova T
- Lehtio L
- Moche M
- Nordlund P
- Nyman T
- Ogg D
- Persson C
- Sagemark J
- Stenmark P
- Sundstrom M
- Thorsell AG
- Tresaugues L
- Weigelt J
- Welin M
- Van den Berg S
