1cd8: Difference between revisions

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[[Image:1cd8.jpg|left|200px]]
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[[Image:1cd8.png|left|200px]]


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{{STRUCTURE_1cd8|  PDB=1cd8  |  SCENE=  }}  
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'''CRYSTAL STRUCTURE OF A SOLUBLE FORM OF THE HUMAN T CELL CO-RECEPTOR CD8 AT 2.6 ANGSTROMS RESOLUTION'''
===CRYSTAL STRUCTURE OF A SOLUBLE FORM OF THE HUMAN T CELL CO-RECEPTOR CD8 AT 2.6 ANGSTROMS RESOLUTION===




==Overview==
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A secreted fragment of the extracellular portion of human CD8 alpha has been expressed in CHO cells, and a deglycosylated and proteolyzed form of this fragment has been crystallized. We report here the crystal structure of this fragment as refined at 2.6 A resolution. The structure was solved by molecular replacement using a superposition of ten variable domains from immunoglobulin light chains as the search model. Only the N-terminal 114 amino acids of CD8 alpha are visible in the electron density maps. The domain formed by these residues possesses a fold typical of immunoglobulin variable domains and associates to form Fv-like homodimers.
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{{ABSTRACT_PUBMED_1547508}}


==About this Structure==
==About this Structure==
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[[Category: Leahy, D J.]]
[[Category: Leahy, D J.]]
[[Category: Surface glycoprotein]]
[[Category: Surface glycoprotein]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 12:36:06 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 20:34:54 2008''

Revision as of 17:34, 30 June 2008

File:1cd8.png

Template:STRUCTURE 1cd8

CRYSTAL STRUCTURE OF A SOLUBLE FORM OF THE HUMAN T CELL CO-RECEPTOR CD8 AT 2.6 ANGSTROMS RESOLUTION

Template:ABSTRACT PUBMED 1547508

About this Structure

1CD8 is a Single protein structure. Full crystallographic information is available from OCA.

Reference

Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 A resolution., Leahy DJ, Axel R, Hendrickson WA, Cell. 1992 Mar 20;68(6):1145-62. PMID:1547508

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