5non: Difference between revisions

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<StructureSection load='5non' size='340' side='right'caption='[[5non]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='5non' size='340' side='right'caption='[[5non]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5non]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NON OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5NON FirstGlance]. <br>
<table><tr><td colspan='2'>[[5non]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thalictrum_flavum_subsp._glaucum Thalictrum flavum subsp. glaucum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NON FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=93H:4-[2-[2-(4-methoxyphenyl)ethylamino]ethyl]benzene-1,2-diol'>93H</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5n8q|5n8q]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=93H:4-[2-[2-(4-methoxyphenyl)ethylamino]ethyl]benzene-1,2-diol'>93H</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-norcoclaurine_synthase (S)-norcoclaurine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.78 4.2.1.78] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5non FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5non OCA], [https://pdbe.org/5non PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5non RCSB], [https://www.ebi.ac.uk/pdbsum/5non PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5non ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5non FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5non OCA], [http://pdbe.org/5non PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5non RCSB], [http://www.ebi.ac.uk/pdbsum/5non PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5non ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NCS_THLFG NCS_THLFG]] Involved in the biosynthesis of the common precursor of all benzylisoquinoline alkaloids such as morphine, sanguinarine, codeine or berberine. Condenses dopamine and 4-hydroxyphenylacetaldehyde.<ref>PMID:17696451</ref> <ref>PMID:17900926</ref> <ref>PMID:18384289</ref>
[https://www.uniprot.org/uniprot/NCS_THLFG NCS_THLFG] Involved in the biosynthesis of the common precursor of all benzylisoquinoline alkaloids such as morphine, sanguinarine, codeine or berberine. Condenses dopamine and 4-hydroxyphenylacetaldehyde.<ref>PMID:17696451</ref> <ref>PMID:17900926</ref> <ref>PMID:18384289</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Hailes, H C]]
[[Category: Thalictrum flavum subsp. glaucum]]
[[Category: Keep, N H]]
[[Category: Hailes HC]]
[[Category: Lichman, B R]]
[[Category: Keep NH]]
[[Category: Pesnot, T]]
[[Category: Lichman BR]]
[[Category: Sula, A]]
[[Category: Pesnot T]]
[[Category: Ward, J M]]
[[Category: Sula A]]
[[Category: Dopamine]]
[[Category: Ward JM]]
[[Category: Lyase]]
[[Category: Pictet spengler condensation]]
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