7cmc: Difference between revisions

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<StructureSection load='7cmc' size='340' side='right'caption='[[7cmc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='7cmc' size='340' side='right'caption='[[7cmc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7cmc]] is a 4 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4p63 4p63]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CMC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7CMC FirstGlance]. <br>
<table><tr><td colspan='2'>[[7cmc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4p63 4p63]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CMC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.46 2.5.1.46] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7cmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cmc OCA], [http://pdbe.org/7cmc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7cmc RCSB], [http://www.ebi.ac.uk/pdbsum/7cmc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7cmc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cmc OCA], [https://pdbe.org/7cmc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cmc RCSB], [https://www.ebi.ac.uk/pdbsum/7cmc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cmc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DHYS_PYRHO DHYS_PYRHO]] Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.  
[https://www.uniprot.org/uniprot/DHYS_PYRHO DHYS_PYRHO] Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7cmc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7cmc" style="background-color:#fffaf0;"></div>
==See Also==
*[[Deoxyhypusine synthase|Deoxyhypusine synthase]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Transferase]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Gai, Z Q]]
[[Category: Gai ZQ]]
[[Category: Okada, C]]
[[Category: Okada C]]
[[Category: Yao, M]]
[[Category: Yao M]]
[[Category: Yu, J]]
[[Category: Yu J]]
[[Category: Deoxyhypusine synthase]]
[[Category: If5a]]
[[Category: Nad+]]
Retrieved from "https://proteopedia.org/7cmc"