Sandbox GGC11: Difference between revisions

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==Your Heading Here (maybe something like 'Structure')==
==Your Heading Here (maybe something like 'Structure')==
<StructureSection load='2M2D' size='340' side='right' caption='Caption for this structure' scene=''>
<StructureSection load='6T1R' size='340' side='right' caption='Caption for this structure' scene=''>
This is a default text for your page '''Sandbox GGC11'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
This is a default text for your page '''Sandbox GGC11'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.


== Function ==
== Function ==
 
This protein contributes to the transparency and refractive index of the eye lens. Alpha- Crystallin can act as chaperones preventing the aggregation of various proteins. 
== Disease ==
== Disease ==
Systemic Lupus Erythematosus 2 (SLEB2)
Cataracts 9, multiple types
This disease is caused by mutations affecting the eye lens. This is an opacification of the crystalline sense of the eye, in most instances, may lead to impairment or blindness.
== Relevance ==
== Relevance ==