Sandbox GGC3: Difference between revisions
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== Function == | == Function == | ||
SARS-Cov-2 utilizes the S-protein to facilitate attachment to host cell surface membranes. | |||
== Disease == | == Disease == | ||
This protein is related to the SARS-cov-2 | This protein is related to the SARS-cov-2 | ||
== Relevance == | == Relevance == | ||
The S-protein of SARS-CoV-2 expressed by the ORF1b gene is trimeric in structure, where each monomer is 180 kDa in size and has two main subunits, an S1 and an S2 subunit. S1 subunit attaches itself to the host cell angiotensin-converting enzyme 2 (ACE2) transmembrane protein. S2 subunit acts in the fusion process of the S-protein which is done by the cleavage protease transmembrane serine or furin. | |||
== Structural highlights == | == Structural highlights == | ||
