1coo: Difference between revisions

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[[Image:1coo.~~gif~~|left|200px]]

[[Image:1coo.png|left|200px]]

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~~'''~~THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT~~'''~~

===THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT===

~~==Overview==~~

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The ~~structure of~~ the ~~carboxyl-terminal domain of~~ the ~~Escherichia coli RNA polymerase alpha subunit~~ (~~alpha CTD~~), ~~which~~ is ~~regarded as~~ the ~~contact site for transcription activator proteins and for the promoter UP element, was determined by nuclear magnetic resonance spectroscopy~~. ~~Its compact structure of four helices and two long arms enclosing its hydrophobic core shows a folding topology distinct from those of other DNA~~-~~binding proteins. The UP element binding site was found on the surface comprising helix 1, the amino~~-~~terminal end of helix 4, and the preceding loop. Mutation experiments indicated that the contact sites for transcription activator proteins are also on the same surface.~~

The line below this paragraph, {{ABSTRACT_PUBMED_7491496}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 7491496 is the PubMed ID number.

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==About this Structure==

1COO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA].

1COO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA].

==Reference==

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[[Category: Yamazaki, T.]]

[[Category: Transcription regulation]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May 2 12~~:57:16 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:01:52 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1coo.gif|left|200px]]
+{{Seed}}
+[[Image:1coo.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_1coo|  PDB=1coo  |  SCENE=  }}
-'''THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT'''
+===THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT===
-==Overview==
+<!--
-The structure of the carboxyl-terminal domain of the Escherichia coli RNA polymerase alpha subunit (alpha CTD), which is regarded as the contact site for transcription activator proteins and for the promoter UP element, was determined by nuclear magnetic resonance spectroscopy. Its compact structure of four helices and two long arms enclosing its hydrophobic core shows a folding topology distinct from those of other DNA-binding proteins. The UP element binding site was found on the surface comprising helix 1, the amino-terminal end of helix 4, and the preceding loop. Mutation experiments indicated that the contact sites for transcription activator proteins are also on the same surface.
+The line below this paragraph, {{ABSTRACT_PUBMED_7491496}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 7491496 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_7491496}}
 ==About this Structure==
-COO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA].
+COO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1COO OCA].
 ==Reference==
@@ Line 30: / Line 34: @@
 [[Category: Yamazaki, T.]]
 [[Category: Transcription regulation]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 12:57:16 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:01:52 2008''