User:Jordan Scott/Sandbox RNA polII: Difference between revisions

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The Discovery and Isolation of RNA Polymerase by Jerard Hurwitz
The Discovery and Isolation of RNA Polymerase by Jerard Hurwitz


 
RNA Polymerase was first isolated y Jerard Hurwitz in 1960. Prior to this, there was research in the synthesis of RNA. One enzyme that was initally thought to synthesize RNA, known as polynucleotide phosphorylase, was isolated but it was discovered to be involved in the degradation of RNA.
== Structural Components ==
== Structural Components ==


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(D)The Discovery and Isolation of RNA Polymerase by Jerard Hurwitz
(D)The Discovery and Isolation of RNA Polymerase by Jerard Hurwitz
(E)Multiple forms of DNA-dependent RNA polymerase in eukaryotic organisms
Bushnell, D. A.; Westover, K. D.; Davis, R. E.; Kornberg, R. D. Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms. Science. 2004, 303, 983-988
Bushnell, D. A.; Westover, K. D.; Davis, R. E.; Kornberg, R. D. Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms. Science. 2004, 303, 983-988