5vei: Difference between revisions
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<StructureSection load='5vei' size='340' side='right'caption='[[5vei]], [[Resolution|resolution]] 1.33Å' scene=''> | <StructureSection load='5vei' size='340' side='right'caption='[[5vei]], [[Resolution|resolution]] 1.33Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5vei]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4igz 4igz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VEI OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5vei]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4igz 4igz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5VEI FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.33Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5vei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vei OCA], [https://pdbe.org/5vei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5vei RCSB], [https://www.ebi.ac.uk/pdbsum/5vei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5vei ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/SRBS2_HUMAN SRBS2_HUMAN] Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.<ref>PMID:9211900</ref> <ref>PMID:12475393</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Bountra | [[Category: Bountra C]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Gu | [[Category: Gu J]] | ||
[[Category: Huang | [[Category: Huang H]] | ||
[[Category: Liu | [[Category: Liu K]] | ||
[[Category: Liu | [[Category: Liu Y]] | ||
[[Category: Min | [[Category: Min J]] | ||
[[Category: Sidhu SS]] | |||
[[Category: Sidhu | [[Category: Tempel W]] | ||
[[Category: Tempel | |||
Latest revision as of 13:47, 4 October 2023
Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
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