Proteinase: Difference between revisions

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</StructureSection>
</StructureSection>
==3D structures of proteinase==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*'''Proteinase A or saccharopepsin'''
**[[2jxr]], [[1fmu]], [[1fmx]] – yPRO - yeast<br />
**[[1dp5]], [[1dpj]], [[1g0v]] - yPRO + polypeptide inhibitor IA3<br />
**[[1fq4]], [[1fq5]], [[1fq6]], [[1fq7]], [[1fq8]] - yPRO + inhibitor<br />
**[[2sga]] – SgPRO – ''Streptomyces griseus''<br />
**[[1sgc]] - SgPRO + chymostatin A<br />
**[[3sga]], [[4sga]], [[5sga]] - SgPRO + polypeptide inhibitor<br />
**[[4fvd]] – hevPRO 2A + peptide – human enterovirus <br />
**[[4fvb]] – hevPRO 2A (mutant) <br />
*'''Proteinase B'''
**[[3sgb]] – SgPRO + turkey ovomucoid inhibitor<br />
**[[1sgp]], [[1sgq]], [[1sgr]], [[1cso]], [[1ct0]], [[1ct2]], [[1ct4]], [[1ds2]], [[2sgp]], [[2nu3]], [[2nu4]] – SgPRO + turkey ovomucoid inhibitor (mutant)<br />
**[[4sgb]] - SgPRO + potato inhibitor
*'''Proteinase K'''
**[[2prk]], [[1cnm]], [[1egq]], [[2id8]], [[2g4v]], [[2v8b]], [[3gt3]], [[3gt4]], [[3d9q]], [[3ddz]], [[3de0]], [[3de1]], [[3de2]], [[3de3]], [[3de4]], [[3de5]], [[3de6]], [[3de7]], [[3dvq]], [[3dvr]], [[3dvs]], [[3dw1]], [[3dw3]], [[3dwe]], [[3i2y]], [[3i30]], [[3i37]], [[3i34]], [[3l1k]], [[3aj8]], [[3aj9]], [[3q40]], [[3q5g]], [[3qmp]], [[4b5l]], [[4fon]], [[6rzp]], [[6qf1]], [[6pu5]], [[6pu4]], [[6pkt]], [[6pks]], [[6pkr]], [[6pkq]], [[6pkp]], [[6pko]], [[6pkn]], [[6pkm]], [[6pkl]], [[6pkk]], [[6pkj]], [[6n4u]], [[6mh6]], [[6fjs]], [[6clb]], [[6cla]], [[6cl9]], [[6cl8]], [[6cl7]], [[5wjh]], [[5wjg]], [[5whw]], [[5uvl]], [[6txg]], [[6pq0]], [[6pq4]], [[6k2v]], [[6k2x]], [[6k2w]], [[6k2p]], [[6k2r]], [[6k2t]], [[6k2s]], [[6v8r]], [[6law]] – EaPRO + Ca – ''Engyodontium album'' <br />
**[[1ic6]], [[6qxv]] – EaPRO (mutant) + Ca  <br />
**[[1ptk]], [[1ht3]] – EaPRO + Ca + Hg <br />
**[[2pkc]] – EaPRO + Na  <br />
**[[5wrc]] – EaPRO + Pr  <br />
**[[4dj5]], [[4woc]], [[4wob]] – EaPRO  <br />
*Proteinase K complex with peptide
**[[3prk]], [[1p7v]], [[1p7w]] – EaPRO + Ca + peptide inhibitor  <br />
**[[1bjr]], [[2dqk]], [[2duj]] – EaPRO + Ca + lactoferrin peptide  <br />
**[[2hd4]] – EaPRO + Ca + lactoferrin peptide inhibitor<br />
**[[2dp4]], [[3ptl]] – EaPRO + lactoferrin peptide  <br />
**[[1pek]], [[1pfg]], [[4zar]] – EaPRO + peptide inhibitor  <br />
**[[1pj8]] – EaPRO + Hg + substrate analog peptide  <br />
**[[2hpz]], [[2pq2]], [[6kkf]] – EaPRO + Ca + peptide  <br />
**[[3osz]] – EaPRO + Ca + antimicrobial peptide  <br />
**[[2b6n]] – PRO + tripeptide - ''Serratia''<br />
*Proteinase K complex with small molecule
**[[2pwb]] – EaPRO + Ca + coumarin  <br />
**[[2pyz]] – EaPRO + Ca + auramine  <br />
**[[2pwa]] – EaPRO + Ca + alanine boronic acid  <br />
**[[1oyo]] – EaPRO + Ca + melanin monomer  <br />
**[[3dyb]] – EaPRO + Ca + digalacturonic acid  <br />
**[[6rvg]], [[6rve]], [[6ruw]], [[6run]], [[6ruk]], [[6ruh]], [[6rug]] – EaPRO + keggin derivative <br />
*'''Proteinase 3C'''
**[[1qa7]] – PRO – Hepatitis virus<br />
**[[2vb0]], [[3zyd]] - PRO – Coxsakievirus<br />
**[[3zye]] – csvPRO (mutant) <br />
**[[3zzd]], [[3zzc]], [[3zza]], [[3zzb]], [[3zz8]], [[3zz9]], [[3zz7]], [[3zz5]], [[3zz3]], [[3zz4]] – csvPRO (mutant) + inhibitor <br />
**[[4ghq]] – hevPRO  <br />
**[[4ght]] – hevPRO + common cold drug  <br />
**[[5c1u]], [[5c1x]], [[5c1y]], [[5c20]], [[5dp9]], [[5dp3]], [[5dp5]], [[5dp8]], [[5dp7]], [[5dpa]], [[5dp4]], [[5dp6]] – PRO + inhibitor – Enterovirus<br />
*'''H2-Proteinase'''
**[[1wni]] – PRO – ''Trimeresurus flavoviridis''
*'''Aspartic Proteinase'''
**[[1fq4]] - yPRO + inhibitor<br />
**[[2asi]] – PRO – ''Rhizomucor miehei''<br />
**[[2apr]] – RmPRO – ''Rhizopus microsporus''<br />
**[[3apr]] - RmPRO + reduced peptide inhibitor<br />
**[[5apr]], [[4apr]] - RmPRO + renin inhibitor<br />
**[[6apr]] - RmPRO + pepstatin<br />
**[[1zap]], [[2h6s]] – CaPRO – ''Candida albicans''<br />
**[[1eag]] – CaPRO + inhibitor <br />
**[[1izd]] - AoPRO – ''Aspergillus oryzae''<br />
**[[1ize]] - AoPRO + polypeptide-statin inhibitor<br />
**[[1j71]] - PRO + polypeptide inhibitor – ''Candida tropicalis''<br />
**[[1wkr]] - PRO + polypeptide-statin inhibitor – ''Irpex lacteus''<br />
**[[3c9x]] - TrPRO – ''Trichoderma reesi''<br />
**[[3emy]] - TrPRO + pepstatin<br />
*'''Aspartic Proteinase Endothiapepsin'''
**[[3urj]], [[1oew]], [[4ape]] - CpPRO – ''Cryphonectria parasitica''<br />
**[[4er4]], [[1eed]], [[2er7]], [[5er1]] - CpPRO + renin inhibitor<br />
**[[1epo]], [[1gvv]], [[2jji]], [[2jjj]], [[1epr]], [[1epq]], [[1epp]], [[1epn]], [[1epm]], [[1epl]], [[1gvw]], [[1gvt]], [[1gvx]], [[1gvu]], [[1oex]], [[3er3]], [[4er1]], [[6scv]], [[6ron]], [[6rsv]], [[1ent]] - CpPRO + inhibitor<br />
**[[3uri]], [[3url]], [[1er8]], [[2er6]], [[4lp9]], [[5er2]], [[3er5]] - CpPRO + peptide inhibitor<br />
**[[2vs2]], [[1gkt]] - CpPRO + inhibitor - Neutron diffraction<br />
**[[2er0]], [[2er9]] - CpPRO + statin-inhibitor<br />
**[[4er2]] - CpPRO + pepstatin<br />
*'''Aspartic proteinase saccharopepsin'''
**[[2jxr]], [[1fmu]], [[1fmx]] – yPRO - yeast<br />
**[[1dp5]], [[1dpj]], [[1g0v]] - yPRO + polypeptide inhibitor IA3<br />
**[[1fq4]], [[1fq5]], [[1fq6]], [[1fq7]], [[1fq8]] - yPRO + inhibitor<br />
*'''Cysteine Proteinase''' or '''gingipain'''
**[[2e03]], [[2e02]], [[2e01]], [[2e00]], [[2dzz]], [[2dzy]] – yPRO 1 (mutant) <br />
**[[2hrv]] – PRO 2A – human rhinovirus<br />
**[[3m1h]], [[4itc]] – PgPRO adhesion domain residues 982-1154 – ''Porphyromonas gingivalis'' <br />
**[[4rbm]], [[4tkx]] – PgPRO catalytic domain residues 229-683<br />
**[[6i9a]] – PgPRO catalytic domain + inhibitor<br />
**[[5mun]] – PgPRO residues 20-228 <br />
**[[2fo5]] – PRO residues 133-356 + leupeptin – ''Hordenum vulgare'' <br />
**[[1x9y]] – SaPRO – ''Staphylococcus aureus'' <br />
**[[1y4h]], [[1pxv]] – SaPRO + PRO inhibitor <br />
**[[6p4e]] – PRO + inhibitor – ''Leishmnia mexicana'' <br />
*'''Cysteine Proteinase''' or '''falcipain'''
**[[2ghu]] – PfPRO-2 – ''Plasmodium falciparum'' <br />
**[[3bpf]], [[6ssz]], [[6jw9]] – PfPRO-2 + inhibitor<br />
**[[3pnr]] – PfPRO-2 + PblCP-C<br />
**[[1yvb]] – PfPRO-2 + cystatin<br />
**[[2oul]] – PfPRO-2 + chagasin<br />
**[[3bpm]] – PfPRO-3 + leupeptin<br />
**[[3bwk]] – PfPRO-3 + inhibitor<br />
*'''Serine Proteinase'''
**[[5m3n]], [[1lcy]] – hPRO HTRA2 – human <br />
**[[5fht]], [[5m3o]], [[5tny]], [[5tnz]], [[5to0]], [[5to1]], [[5wyn]] – hPRO HTRA2 (mutant) <br />
**[[3s9a]], [[3s9b]] – RvPRO – Siamese Russell’s viper<br />
**[[3s9c]], [[3sbk]] – RvPRO + human factor V polypeptide<br />
**[[1po0]], [[1op2]] – PRO – Chinese moccasin <br />
**[[1qy8]] – SaPRO <br />
**[[1mbm]] – PRO – equine arteritis virus <br />
**[[1dbi]] – PRO – ''Bacillus'' <br />>
**[[1ga1]], [[1ga4]], [[1ga6]], [[1nlu]] – PsPRO + iodotyrostatin fragment – ''Pseudomonas''<br />
**[[6m8w]], [[6m8y]], [[6m8f]], [[6m9c]], [[6m9d]] - PsPRO + polypeptide inhibitor<br />
**[[1s2n]], [[1sh7]] – PRO – ''Vibrio''<br />
*'''Astacin'''
**[[1iac]], [[1iad]], [[1iae]], [[1iab]], [[1iaa]], [[1ast]] – cAst – crayfish <br />
**[[3lq0]] – cpro-Ast <br />
**[[6saz]], [[6ht9]] – cAst + fetuin-B <br />
**[[1qji]], [[1qjj]] – cAst + inhibitor <br />
}}


== References ==
== References ==
<references/>
<references/>
[[Category: Topic Page]]
[[Category: Topic Page]]
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