4ytk: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[4ytk]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Baker's_yeast Baker's yeast~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=4YTK FirstGlance]. <br>

<table><tr><td colspan='2'>[[4ytk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YTK FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPT5, YML010W, YM9571.08 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ytk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytk OCA], [https://pdbe.org/4ytk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ytk RCSB], [https://www.ebi.ac.uk/pdbsum/4ytk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ytk ProSAT]</span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=4ytk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytk OCA], [~~http~~://pdbe.org/4ytk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4ytk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4ytk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4ytk ProSAT]</span></td></tr>

</table>

== Function ==

[~~[http~~://www.uniprot.org/uniprot/SPT5_YEAST SPT5_YEAST]] The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.<ref>PMID:12554661</ref> <ref>PMID:12556496</ref> <ref>PMID:15780939</ref> <ref>PMID:16172632</ref> <ref>PMID:9450930</ref>

[https://www.uniprot.org/uniprot/SPT5_YEAST SPT5_YEAST] The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.<ref>PMID:12554661</ref> <ref>PMID:12556496</ref> <ref>PMID:15780939</ref> <ref>PMID:16172632</ref> <ref>PMID:9450930</ref>

== Publication Abstract from PubMed ==

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__TOC__

</StructureSection>

~~[[Category: Baker's yeast]]~~

[[Category: Large Structures]]

[[Category: Fu, J]]

[[Category: Saccharomyces cerevisiae S288C]]

[[Category: Hartzog~~, G A~~]]

[[Category: Fu J]]

[[Category: Li, S]]

[[Category: Hartzog GA]]

[[Category: Meyer~~, P A~~]]

[[Category: Li S]]

[[Category: Takagi, Y]]

[[Category: Meyer PA]]

[[Category: Yamada, K]]

[[Category: Takagi Y]]

[[Category: Zhang, M]]

[[Category: Yamada K]]

~~[[Category: Elongation]]~~

[[Category: Zhang M]]

~~[[Category: Protein-dna interaction]]~~

~~[[Category: Rna processing]]~~

~~[[Category: Transcription~~]]

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@@ Line 3: / Line 3: @@
 <StructureSection load='4ytk' size='340' side='right'caption='[[4ytk]], [[Resolution|resolution]] 1.09&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4ytk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4YTK FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4ytk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YTK FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPT5, YML010W, YM9571.08 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ytk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytk OCA], [https://pdbe.org/4ytk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ytk RCSB], [https://www.ebi.ac.uk/pdbsum/4ytk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ytk ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4ytk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytk OCA], [http://pdbe.org/4ytk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ytk RCSB], [http://www.ebi.ac.uk/pdbsum/4ytk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ytk ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/SPT5_YEAST SPT5_YEAST]] The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.<ref>PMID:12554661</ref> <ref>PMID:12556496</ref> <ref>PMID:15780939</ref> <ref>PMID:16172632</ref> <ref>PMID:9450930</ref>
+[https://www.uniprot.org/uniprot/SPT5_YEAST SPT5_YEAST] The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.<ref>PMID:12554661</ref> <ref>PMID:12556496</ref> <ref>PMID:15780939</ref> <ref>PMID:16172632</ref> <ref>PMID:9450930</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 25: / Line 24: @@
 __TOC__
 </StructureSection>
-[[Category: Baker's yeast]]
 [[Category: Large Structures]]
-[[Category: Fu, J]]
+[[Category: Saccharomyces cerevisiae S288C]]
-[[Category: Hartzog, G A]]
+[[Category: Fu J]]
-[[Category: Li, S]]
+[[Category: Hartzog GA]]
-[[Category: Meyer, P A]]
+[[Category: Li S]]
-[[Category: Takagi, Y]]
+[[Category: Meyer PA]]
-[[Category: Yamada, K]]
+[[Category: Takagi Y]]
-[[Category: Zhang, M]]
+[[Category: Yamada K]]
-[[Category: Elongation]]
+[[Category: Zhang M]]
-[[Category: Protein-dna interaction]]
-[[Category: Rna processing]]
-[[Category: Transcription]]