6ire: Difference between revisions

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====

==Complex structure of INAD PDZ45 and NORPA CC-PBM==

== Structural highlights ==

<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a guided tour on the structure components use [~~http~~://proteopedia.org/fgij/fg.htm?mol= FirstGlance].

<table><tr><td colspan='2'>[[6ire]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IRE OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=6IRE FirstGlance].

</td></tr><tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[~~http~~://proteopedia.org/fgij/fg.htm?mol=6ire FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ire OCA], [~~http~~://pdbe.org/6ire PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=6ire RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/6ire PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=6ire ProSAT]</td></tr>

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25Å</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=6ire FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ire OCA], [https://pdbe.org/6ire PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ire RCSB], [https://www.ebi.ac.uk/pdbsum/6ire PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ire ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/PIPA_DROME PIPA_DROME] The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (By similarity). Essential component of the phototransduction pathway (PubMed:2457447). Essential downstream component of a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required for the activation of Cad99C and consequently Cad99C-dependent endosome formation, which is essential for the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection (PubMed:25639794).[UniProtKB:Q9P212]<ref>PMID:2457447</ref> <ref>PMID:25639794</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Drosophila melanogaster]]

[[Category: Large Structures]]

[[Category: ~~Z-disk~~]]

[[Category: Deng X]]

[[Category: Li J]]

[[Category: Liu W]]

[[Category: Ye F]]

[[Category: Zhang M]]

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-====
+==Complex structure of INAD PDZ45 and NORPA CC-PBM==
-<StructureSection load='6ire' size='340' side='right'caption='[[6ire]]' scene=''>
+<StructureSection load='6ire' size='340' side='right'caption='[[6ire]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6ire]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IRE FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6ire FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ire OCA], [http://pdbe.org/6ire PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ire RCSB], [http://www.ebi.ac.uk/pdbsum/6ire PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ire ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ire FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ire OCA], [https://pdbe.org/6ire PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ire RCSB], [https://www.ebi.ac.uk/pdbsum/6ire PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ire ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/PIPA_DROME PIPA_DROME] The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (By similarity). Essential component of the phototransduction pathway (PubMed:2457447). Essential downstream component of a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required for the activation of Cad99C and consequently Cad99C-dependent endosome formation, which is essential for the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection (PubMed:25639794).[UniProtKB:Q9P212]<ref>PMID:2457447</ref> <ref>PMID:25639794</ref>
+== References ==
+<references/>
 __TOC__
 </StructureSection>
+[[Category: Drosophila melanogaster]]
 [[Category: Large Structures]]
-[[Category: Z-disk]]
+[[Category: Deng X]]
+[[Category: Li J]]
+[[Category: Liu W]]
+[[Category: Ye F]]
+[[Category: Zhang M]]