5z5q: Difference between revisions

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==Nukacin ISK-1 in active state==
==Nukacin ISK-1 in active state==
<StructureSection load='5z5q' size='340' side='right'caption='[[5z5q]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='5z5q' size='340' side='right'caption='[[5z5q]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5z5q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_warneri Staphylococcus warneri]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z5Q OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5Z5Q FirstGlance]. <br>
<table><tr><td colspan='2'>[[5z5q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_warneri Staphylococcus warneri]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Z5Q FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=DBU:(2Z)-2-AMINOBUT-2-ENOIC+ACID'>DBU</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=DBB:D-ALPHA-AMINOBUTYRIC+ACID'>DBB</scene>, <scene name='pdbligand=DBU:(2Z)-2-AMINOBUT-2-ENOIC+ACID'>DBU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5z5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z5q OCA], [http://pdbe.org/5z5q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z5q RCSB], [http://www.ebi.ac.uk/pdbsum/5z5q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z5q ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5z5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z5q OCA], [https://pdbe.org/5z5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5z5q RCSB], [https://www.ebi.ac.uk/pdbsum/5z5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5z5q ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LANNA_STAWA LANNA_STAWA]] Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria, such as Lactobacillus sakei, Leuconostoc mesenteroides and Pediococcus pentosaceus. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.<ref>PMID:16233732</ref> <ref>PMID:16957223</ref> [REFERENCE:4]  
[https://www.uniprot.org/uniprot/LANNA_STAWA LANNA_STAWA] Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria, such as Lactobacillus sakei, Leuconostoc mesenteroides and Pediococcus pentosaceus. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.<ref>PMID:16233732</ref> <ref>PMID:16957223</ref> [REFERENCE:4]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Staphylococcus warneri]]
[[Category: Staphylococcus warneri]]
[[Category: Fujinami, D]]
[[Category: Fujinami D]]
[[Category: Kohda, D]]
[[Category: Kohda D]]
[[Category: Antibiotic]]
[[Category: Lantibiotic]]