5z9y: Difference between revisions

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<StructureSection load='5z9y' size='340' side='right'caption='[[5z9y]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
<StructureSection load='5z9y' size='340' side='right'caption='[[5z9y]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5z9y]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z9Y OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5Z9Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[5z9y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Z9Y FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXP:1-DEOXY-D-XYLULOSE-5-PHOSPHATE'>DXP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiazole_synthase Thiazole synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.1.10 2.8.1.10] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXP:1-DEOXY-D-XYLULOSE-5-PHOSPHATE'>DXP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5z9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z9y OCA], [http://pdbe.org/5z9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z9y RCSB], [http://www.ebi.ac.uk/pdbsum/5z9y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z9y ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5z9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z9y OCA], [https://pdbe.org/5z9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5z9y RCSB], [https://www.ebi.ac.uk/pdbsum/5z9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5z9y ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/THIG_MYCTU THIG_MYCTU]] Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.  
[https://www.uniprot.org/uniprot/THIG_MYCTU THIG_MYCTU] Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Thiazole synthase]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Cui, P]]
[[Category: Cui P]]
[[Category: Huang, M]]
[[Category: Huang M]]
[[Category: Li, J]]
[[Category: Li J]]
[[Category: Yang, X]]
[[Category: Yang X]]
[[Category: Zhang, B]]
[[Category: Zhang B]]
[[Category: Zhang, J]]
[[Category: Zhang J]]
[[Category: Zhang, W]]
[[Category: Zhang W]]
[[Category: Zhang, Y]]
[[Category: Zhang Y]]
[[Category: Zhao, Y]]
[[Category: Zhao Y]]
[[Category: Alpha-beta barrel]]
[[Category: Biosynthetic protein]]
[[Category: Carbinolamine intermediate]]
[[Category: Covalently bound]]
[[Category: Transferase]]