6w1b: Difference between revisions
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==N-terminal domain of mouse surfactant protein B with bound lipid, Y59A/H79A mutant== | ==N-terminal domain of mouse surfactant protein B with bound lipid, Y59A/H79A mutant== | ||
<StructureSection load='6w1b' size='340' side='right'caption='[[6w1b]]' scene=''> | <StructureSection load='6w1b' size='340' side='right'caption='[[6w1b]], [[Resolution|resolution]] 2.31Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6W1B OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6W1B FirstGlance]. <br> | <table><tr><td colspan='2'>[[6w1b]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6W1B OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6W1B FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6w1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6w1b OCA], [http://pdbe.org/6w1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6w1b RCSB], [http://www.ebi.ac.uk/pdbsum/6w1b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6w1b ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEE:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE'>PEE</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Sftpb, Sftp3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6w1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6w1b OCA], [http://pdbe.org/6w1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6w1b RCSB], [http://www.ebi.ac.uk/pdbsum/6w1b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6w1b ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PSPB_MOUSE PSPB_MOUSE]] Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bodnar | [[Category: Lk3 transgenic mice]] | ||
[[Category: Rapoport | [[Category: Bodnar, N O]] | ||
[[Category: Rapoport, T A]] | |||
[[Category: Lipid transfer]] | |||
[[Category: Lipid-binding]] | |||
[[Category: Saposin-like]] | |||
[[Category: Surfactant protein]] | |||
