1s31: Difference between revisions
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<StructureSection load='1s31' size='340' side='right'caption='[[1s31]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='1s31' size='340' side='right'caption='[[1s31]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1s31]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1s31]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S31 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S31 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.704Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s31 OCA], [https://pdbe.org/1s31 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s31 RCSB], [https://www.ebi.ac.uk/pdbsum/1s31 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s31 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/TUB_HUMAN TUB_HUMAN] Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Abitbol | [[Category: Abitbol M]] | ||
[[Category: Basdevant | [[Category: Basdevant A]] | ||
[[Category: Boutboul | [[Category: Boutboul S]] | ||
[[Category: Carroll | [[Category: Carroll KJ]] | ||
[[Category: Clement | [[Category: Clement K]] | ||
[[Category: Gomez | [[Category: Gomez C]] | ||
[[Category: Nandrot | [[Category: Nandrot E]] | ||
[[Category: Shapiro | [[Category: Shapiro L]] | ||
Latest revision as of 06:12, 23 August 2023
Crystal Structure Analysis of the human Tub protein (isoform a) spanning residues 289 through 561
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