1dfq: Difference between revisions

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[[Image:1dfq.gif|left|200px]]
{{Seed}}
[[Image:1dfq.png|left|200px]]


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{{STRUCTURE_1dfq|  PDB=1dfq  |  SCENE=  }}  
{{STRUCTURE_1dfq|  PDB=1dfq  |  SCENE=  }}  


'''THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH SIALIC ACID'''
===THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH SIALIC ACID===




==Overview==
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The entry of tetanus neurotoxin into neuronal cells proceeds through the initial binding of the toxin to gangliosides on the cell surface. The carboxyl-terminal fragment of the heavy chain of tetanus neurotoxin contains the ganglioside-binding site, which has not yet been fully characterized. The crystal structures of native H(C) and of H(C) soaked with carbohydrates reveal a number of binding sites and provide insight into the possible mode of ganglioside binding.
The line below this paragraph, {{ABSTRACT_PUBMED_10722735}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 10722735 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10722735}}


==About this Structure==
==About this Structure==
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[[Category: Jelly-roll]]
[[Category: Jelly-roll]]
[[Category: Toxin]]
[[Category: Toxin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 13:48:12 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:00:34 2008''