Sandbox Reserved 1653: Difference between revisions
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However, Piezo 1 is implicated in excitatory channels because cation can enter into the cell and lead to membrane [https://en.wikipedia.org/wiki/Depolarization depolarisation] or [https://en.wikipedia.org/wiki/Calcium_signaling calcium dependent signalling pathway] (if Ca2+ enter). <ref name="Adenosine"> DOI 10.3389/fphar.2019.01304 </ref> | However, Piezo 1 is implicated in excitatory channels because cation can enter into the cell and lead to membrane [https://en.wikipedia.org/wiki/Depolarization depolarisation] or [https://en.wikipedia.org/wiki/Calcium_signaling calcium dependent signalling pathway] (if Ca2+ enter). <ref name="Adenosine"> DOI 10.3389/fphar.2019.01304 </ref> | ||
When calcium-dependent signalling pathway is activated, NO can be released by endothelial cells and lead to vasodilation but also, some channels can also | When calcium-dependent signalling pathway is activated, NO can be released by endothelial cells and lead to vasodilation but also, some channels can also | ||
be activated in red blood cells. <ref name="Adenosine"/ | be activated in red blood cells. <ref name="Adenosine"/> | ||
Piezo has a wide variety of functions, but we will focus on the vascularisation. | Piezo has a wide variety of functions, but we will focus on the vascularisation. | ||
