Sandbox Reserved 1656: Difference between revisions
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== Structure == | == Structure == | ||
==== Catalytic domain ==== | |||
It is the catalytic domain which defines the family of the DUB. Indeed, DUBs belonging to the family of cysteine proteases have a catalytic site composed of two or three amino acids (dyads or triads). When the catalytic site is active, it may contain cysteine, histidine, aspartate or asparagine residues. In the case of metalloproteases, the active site is composed of a zinc ion and amino acids such as histidine, aspartate and serine. <ref>https://authors.library.caltech.edu/261/1/AMBpb04.pdf</ref> | It is the catalytic domain which defines the family of the DUB. Indeed, DUBs belonging to the family of cysteine proteases have a catalytic site composed of two or three amino acids (dyads or triads). When the catalytic site is active, it may contain cysteine, histidine, aspartate or asparagine residues. In the case of metalloproteases, the active site is composed of a zinc ion and amino acids such as histidine, aspartate and serine. <ref>https://authors.library.caltech.edu/261/1/AMBpb04.pdf</ref> | ||
