Sandbox Reserved 1656: Difference between revisions
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==== Function ==== | ==== Function ==== | ||
Deubiquitinases or Deubiquitinating enzymes (DUBs) are key enzymes belonging to the vast group of proteases, allowing the degradation of ubiquitin of proteins. These enzymes are thus implicated in the regulation of protein degradation. Indeed, when a protein is going to be degraded, an enzymatic cascade will add a poly-ubiquitin fragment to the protein. This mechanism is called | Deubiquitinases or Deubiquitinating enzymes (DUBs) are key enzymes belonging to the vast group of proteases, allowing the degradation of [https://fr.wikipedia.org/wiki/Ubiquitine ubiquitin] of proteins. These enzymes are thus implicated in the regulation of protein degradation. Indeed, when a protein is going to be degraded, an enzymatic cascade will add a poly-ubiquitin fragment to the protein. This mechanism is called [https://fr.wikipedia.org/wiki/Ubiquitination ubiquitination]. Following this step, mono or poly-ubiquitin is removed from the protein which has been degraded, by deubiquitinase. <ref>PMID:9409543</ref> | ||
==== Families ==== | ==== Families ==== | ||
