Sandbox Reserved 1656: Difference between revisions
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==== Localization ==== | ==== Localization ==== | ||
The localization depends on the DUB we consider. However, the majority of DUBs are found in the nucleus, plasma membrane or/and in secretory and endocytic pathways. For example, in the ubiquitin-specific proteases family, the USP21 is mostly associated with microtubules and the centrosome.<ref>PMID:22298430</ref> | The localization depends on the DUB we consider. However, the majority of DUBs are found in the nucleus, plasma membrane or/and in secretory and endocytic pathways. For example, in the ubiquitin-specific proteases family, the USP21 is mostly associated with microtubules and the centrosome. Thus this deubiquitinase depends on all the physiological mechanisms involving the microtubules. <ref>PMID:22298430</ref> | ||
== Structure == | == Structure == | ||
