Sandbox Reserved 1654: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 24: | Line 24: | ||
***The <scene name='86/868187/Rmm/10'>interdomain linker</scene> takes a helical turn that interacts with residues of the N-terminal extension and with <scene name='86/868187/Rmm/6'>RRM2</scene>. | ***The <scene name='86/868187/Rmm/10'>interdomain linker</scene> takes a helical turn that interacts with residues of the N-terminal extension and with <scene name='86/868187/Rmm/6'>RRM2</scene>. | ||
***<scene name='86/868187/Rmm/1'>Trp331</scene> positions RRM2 relative to RRM1 by inserting its indole ring between the beta sheet and <scene name='86/868187/Rmm/9'>alpha1 helix</scene> of RRM2. | ***<scene name='86/868187/Rmm/1'>Trp331</scene> positions RRM2 relative to RRM1 by inserting its indole ring between the beta sheet and <scene name='86/868187/Rmm/9'>alpha1 helix</scene> of RRM2. | ||
***After the helical turn, the interdomain linker folds in a beta strand which is anti-parallel to the beta2 strand (RRM2). The interdomain linker is therefore a kind of joint for the relative orientation of the two RRMs. | ***After the helical turn, the interdomain linker folds in a <scene name='86/868187/Rmm/11'>beta strand</scene> which is anti-parallel to the beta2 strand (RRM2). The interdomain linker is therefore a kind of joint for the relative orientation of the two RRMs. | ||
== Function == | == Function == | ||
